Cargando…
A Derivative of Differentiation-Inducing Factor-3 Inhibits PAK1 Activity and Breast Cancer Cell Proliferation
Differentiation-inducing factors 1-3 (DIFs 1-3), chlorinated alkylphenones identified in the cellular slime mold Dictyostelium discoideum, are considered anti-tumor agents because they inhibit proliferation of a variety of mammalian tumor cells in vitro. Although the anti-proliferative effects of DI...
Autores principales: | Oladimeji, Peter, Kubohara, Yuzuru, Kikuchi, Haruhisa, Oshima, Yoshiteru, Rusch, Courtney, Skerl, Rebekah, Diakonova, Maria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682050/ https://www.ncbi.nlm.nih.gov/pubmed/26688830 |
Ejemplares similares
-
Properties of a non-bioactive fluorescent derivative of differentiation-inducing factor-3, an anti-tumor agent found in Dictyostelium discoideum
por: Kubohara, Yuzuru, et al.
Publicado: (2014) -
Antimicrobial Activities of Dictyostelium Differentiation-Inducing Factors and Their Derivatives
por: Kubohara, Yuzuru, et al.
Publicado: (2019) -
Evidence that differentiation-inducing factor-1 controls chemotaxis and cell differentiation, at least in part, via mitochondria in D. discoideum
por: Kubohara, Yuzuru, et al.
Publicado: (2017) -
Mitochondria Are the Target Organelle of Differentiation-Inducing Factor-3, an Anti-Tumor Agent Isolated from Dictyostelium Discoideum
por: Kubohara, Yuzuru, et al.
Publicado: (2013) -
Halogen-Substituted Derivatives of Dictyostelium Differentiation-Inducing Factor-1 Suppress Serum-Induced Cell Migration of Human Breast Cancer MDA-MB-231 Cells in Vitro
por: Totsuka, Kyoko, et al.
Publicado: (2019)