Reprogramming of Polycomb-Mediated Gene Silencing in Embryonic Stem Cells by the miR-290 Family and the Methyltransferase Ash1l

Members of the miR-290 family are the most abundantly expressed microRNAs (miRNAs) in mouse embryonic stem cells (ESCs). They regulate aspects of differentiation, pluripotency, and proliferation of ESCs, but the molecular program that they control has not been fully delineated. In the absence of Dic...

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Detalles Bibliográficos
Autores principales: Kanellopoulou, Chryssa, Gilpatrick, Timothy, Kilaru, Gokhul, Burr, Patrick, Nguyen, Cuong K., Morawski, Aaron, Lenardo, Michael J., Muljo, Stefan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682067/
https://www.ncbi.nlm.nih.gov/pubmed/26549848
http://dx.doi.org/10.1016/j.stemcr.2015.10.001

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