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Isolation of Human Colon Stem Cells Using Surface Expression of PTK7

Insertion of reporter cassettes into the Lgr5 locus has enabled the characterization of mouse intestinal stem cells (ISCs). However, low cell surface abundance of LGR5 protein and lack of high-affinity anti-LGR5 antibodies represent a roadblock to efficiently isolate human colonic stem cells (hCoSCs...

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Detalles Bibliográficos
Autores principales:	Jung, Peter, Sommer, Christian, Barriga, Francisco M., Buczacki, Simon J., Hernando-Momblona, Xavier, Sevillano, Marta, Duran-Frigola, Miquel, Aloy, Patrick, Selbach, Matthias, Winton, Douglas J., Batlle, Eduard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682088/ https://www.ncbi.nlm.nih.gov/pubmed/26549850 http://dx.doi.org/10.1016/j.stemcr.2015.10.003

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