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RCAN1 links impaired neurotrophin trafficking to aberrant development of the sympathetic nervous system in Down syndrome

Down syndrome is the most common chromosomal disorder affecting the nervous system in humans. To date, investigations of neural anomalies in Down syndrome have focused on the central nervous system, although dysfunction of the peripheral nervous system is a common manifestation. The molecular and ce...

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Detalles Bibliográficos
Autores principales: Patel, Ami, Yamashita, Naoya, Ascaño, Maria, Bodmer, Daniel, Boehm, Erica, Bodkin-Clarke, Chantal, Ryu, Yun Kyoung, Kuruvilla, Rejji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682116/
https://www.ncbi.nlm.nih.gov/pubmed/26658127
http://dx.doi.org/10.1038/ncomms10119