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Presynaptic hyperpolarization induces a fast analogue modulation of spike-evoked transmission mediated by axonal sodium channels

In the mammalian brain, synaptic transmission usually depends on presynaptic action potentials (APs) in an all-or-none (or digital) manner. Recent studies suggest, however, that subthreshold depolarization in the presynaptic cell facilitates spike-evoked transmission, thus creating an analogue modul...

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Detalles Bibliográficos
Autores principales: Rama, Sylvain, Zbili, Mickaël, Bialowas, Andrzej, Fronzaroli-Molinieres, Laure, Ankri, Norbert, Carlier, Edmond, Marra, Vincenzo, Debanne, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682119/
https://www.ncbi.nlm.nih.gov/pubmed/26657943
http://dx.doi.org/10.1038/ncomms10163