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Presynaptic hyperpolarization induces a fast analogue modulation of spike-evoked transmission mediated by axonal sodium channels
In the mammalian brain, synaptic transmission usually depends on presynaptic action potentials (APs) in an all-or-none (or digital) manner. Recent studies suggest, however, that subthreshold depolarization in the presynaptic cell facilitates spike-evoked transmission, thus creating an analogue modul...
Autores principales: | Rama, Sylvain, Zbili, Mickaël, Bialowas, Andrzej, Fronzaroli-Molinieres, Laure, Ankri, Norbert, Carlier, Edmond, Marra, Vincenzo, Debanne, Dominique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682119/ https://www.ncbi.nlm.nih.gov/pubmed/26657943 http://dx.doi.org/10.1038/ncomms10163 |
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