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Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts

The derivation of genetically modified induced pluripotent stem (iPS) cells typically involves multiple steps, requiring lengthy cell culture periods, drug selection, and several clonal events. We report the generation of gene-targeted iPS cell lines following a single electroporation of patient-spe...

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Detalles Bibliográficos
Autores principales:	Howden, Sara E., Maufort, John P., Duffin, Bret M., Elefanty, Andrew G., Stanley, Edouard G., Thomson, James A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682122/ https://www.ncbi.nlm.nih.gov/pubmed/26584543 http://dx.doi.org/10.1016/j.stemcr.2015.10.009

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