Inflammatory Eicosanoids Increase Amyloid Precursor Protein Expression via Activation of Multiple Neuronal Receptors

Senile plaques comprised of Aβ peptides are a hallmark of Alzheimer’s disease (AD) brain, as are activated glia that release inflammatory molecules, including eicosanoids. Previous studies have demonstrated that amyloid precursor protein (APP) and Aβ levels can be increased through activation of thr...

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Detalles Bibliográficos
Autores principales: Herbst-Robinson, Katie J., Liu, Li, James, Michael, Yao, Yuemang, Xie, Sharon X., Brunden, Kurt R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682150/
https://www.ncbi.nlm.nih.gov/pubmed/26672557
http://dx.doi.org/10.1038/srep18286

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