Reduced Adult Hippocampal Neurogenesis and Cognitive Impairments following Prenatal Treatment of the Antiepileptic Drug Valproic Acid

Prenatal exposure to valproic acid (VPA), an established antiepileptic drug, has been reported to impair postnatal cognitive function in children born to VPA-treated epileptic mothers. However, how these defects arise and how they can be overcome remain unknown. Using mice, we found that comparable...

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Detalles Bibliográficos
Autores principales: Juliandi, Berry, Tanemura, Kentaro, Igarashi, Katsuhide, Tominaga, Takashi, Furukawa, Yusuke, Otsuka, Maky, Moriyama, Noriko, Ikegami, Daigo, Abematsu, Masahiko, Sanosaka, Tsukasa, Tsujimura, Keita, Narita, Minoru, Kanno, Jun, Nakashima, Kinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682151/
https://www.ncbi.nlm.nih.gov/pubmed/26677766
http://dx.doi.org/10.1016/j.stemcr.2015.10.012

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