SCF(β-TRCP) promotes cell growth by targeting PR-Set7/Set8 for degradation

The Set8/PR-Set7/KMT5a methyltransferase plays critical roles in governing transcriptional regulation, cell cycle progression and tumorigenesis. Although CRL4(Cdt2) was reported to regulate Set8 stability, deleting the PIP motif only led to partial resistance to ultraviolet-induced degradation of Se...

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Detalles Bibliográficos
Autores principales: Wang, Zhiwei, Dai, Xiangpeng, Zhong, Jiateng, Inuzuka, Hiroyuki, Wan, Lixin, Li, Xiaoning, Wang, Lixia, Ye, Xiantao, Sun, Liankun, Gao, Daming, Zou, Lee, Wei, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682171/
https://www.ncbi.nlm.nih.gov/pubmed/26666832
http://dx.doi.org/10.1038/ncomms10185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682171/
https://www.ncbi.nlm.nih.gov/pubmed/26666832
http://dx.doi.org/10.1038/ncomms10185

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