Cargando…
HIV-1 CCR5 gene therapy will fail unless it is combined with a suicide gene
Highly active antiretroviral therapy (ART) has successfully turned Human immunodeficiency virus type 1 (HIV-1) from a deadly pathogen into a manageable chronic infection. ART is a lifelong therapy which is both expensive and toxic, and HIV can become resistant to it. An alternative to lifelong ART i...
Autores principales: | Pandit, Aridaman, de Boer, Rob J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682191/ https://www.ncbi.nlm.nih.gov/pubmed/26674113 http://dx.doi.org/10.1038/srep18088 |
Ejemplares similares
-
Combination gene therapy for HIV using a conditional suicidal gene with CCR5 knockout
por: Mehmetoglu-Gurbuz, Tugba, et al.
Publicado: (2021) -
Humancentric: technology fails unless it means something to someone
por: Saunders, Mike
Publicado: (2020) -
Reliable reconstruction of HIV-1 whole genome haplotypes reveals clonal interference and genetic hitchhiking among immune escape variants
por: Pandit, Aridaman, et al.
Publicado: (2014) -
Differential Trends in the Codon Usage Patterns in HIV-1 Genes
por: Pandit, Aridaman, et al.
Publicado: (2011) -
Stochastic Inheritance of Division and Death Times Determines the Size and Phenotype of CD8(+) T Cell Families
por: Pandit, Aridaman, et al.
Publicado: (2019)