Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells

We demonstrate that dissociated human pluripotent stem cells (PSCs) are intrinsically programmed to form lumens. PSCs form two-cell cysts with a shared apical domain within 20 hr of plating; these cysts collapse to form monolayers after 5 days. Expression of pluripotency markers is maintained throug...

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Detalles Bibliográficos
Autores principales: Taniguchi, Kenichiro, Shao, Yue, Townshend, Ryan F., Tsai, Yu-Hwai, DeLong, Cynthia J., Lopez, Shawn A., Gayen, Srimonta, Freddo, Andrew M., Chue, Deming J., Thomas, Dennis J., Spence, Jason R., Margolis, Benjamin, Kalantry, Sundeep, Fu, Jianping, O’Shea, K. Sue, Gumucio, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682207/
https://www.ncbi.nlm.nih.gov/pubmed/26626176
http://dx.doi.org/10.1016/j.stemcr.2015.10.015

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