Cargando…
Metformin Acts on Two Different Molecular Pathways to Enhance Adult Neural Precursor Proliferation/Self-Renewal and Differentiation
The recruitment of endogenous adult neural stem cells for brain repair is a promising regenerative therapeutic strategy. This strategy involves stimulation of multiple stages of adult neural stem cell development, including proliferation, self-renewal, and differentiation. Currently, there is a lack...
Autores principales: | Fatt, Michael, Hsu, Karolynn, He, Ling, Wondisford, Fredric, Miller, Freda D., Kaplan, David R., Wang, Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682208/ https://www.ncbi.nlm.nih.gov/pubmed/26677765 http://dx.doi.org/10.1016/j.stemcr.2015.10.014 |
Ejemplares similares
-
Activating Endogenous Neural Precursor Cells Using Metformin Leads to Neural Repair and Functional Recovery in a Model of Childhood Brain Injury
por: Dadwal, Parvati, et al.
Publicado: (2015) -
microRNA regulation of neural precursor self-renewal and differentiation
por: Hudish, Laura I, et al.
Publicado: (2014) -
Stable STIM1 Knockdown in Self-Renewing Human Neural Precursors Promotes Premature Neural Differentiation
por: Gopurappilly, Renjitha, et al.
Publicado: (2018) -
Restoration of hippocampal neural precursor function by ablation of senescent cells in the aging stem cell niche
por: Fatt, Michael P., et al.
Publicado: (2022) -
Toll-like receptors 2 and 4 differentially regulate the self-renewal and differentiation of spinal cord neural precursor cells
por: Sanchez-Petidier, Marina, et al.
Publicado: (2022)