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Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes

Stem cell-derived somatic cells represent an unlimited resource for basic and translational science. Although promising, there are significant hurdles that must be overcome. Our focus is on the generation of the major cell type of the human liver, the hepatocyte. Current protocols produce variable p...

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Detalles Bibliográficos
Autores principales: Cameron, Kate, Tan, Rosanne, Schmidt-Heck, Wolfgang, Campos, Gisela, Lyall, Marcus J., Wang, Yu, Lucendo-Villarin, Baltasar, Szkolnicka, Dagmara, Bates, Nicola, Kimber, Susan J., Hengstler, Jan G., Godoy, Patricio, Forbes, Stuart J., Hay, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682209/
https://www.ncbi.nlm.nih.gov/pubmed/26626180
http://dx.doi.org/10.1016/j.stemcr.2015.10.016