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Decreased PCSK9 expression in human hepatocellular carcinoma

BACKGROUND: The management of hepatocellular carcinoma (HCC) is limited by the lack of adequate screening biomarkers and chemotherapy. In response, there has been much interest in tumor metabolism as a therapeutic target. PCSK9 stimulates internalization of the LDL-receptor, decreases cholesterol up...

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Detalles Bibliográficos
Autores principales:	Bhat, Mamatha, Skill, Nicolas, Marcus, Victoria, Deschenes, Marc, Tan, Xianming, Bouteaud, Jeanne, Negi, Sarita, Awan, Zuhier, Aikin, Reid, Kwan, Janet, Amre, Ramila, Tabaries, Sebastien, Hassanain, Mazen, Seidah, Nabil G., Maluccio, Mary, Siegel, Peter, Metrakos, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682218/ https://www.ncbi.nlm.nih.gov/pubmed/26674961 http://dx.doi.org/10.1186/s12876-015-0371-6

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