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Effect of the molecular targeted drug, erlotinib, against endometrial cancer expressing high levels of epidermal growth factor receptor

BACKGROUND: The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, erlotinib, has been clinically applied for the treatment of a variety of tumors with EGFR overexpression. A phase II clinical study of erlotinib (NCIC IND-148) for recurrent or metastatic endometrial carcinoma (EC) re...

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Detalles Bibliográficos
Autores principales:	Nishimura, Toshio, Nakamura, Kazuto, Yamashita, Soichi, Ikeda, Sadatomo, Kigure, Keiko, Minegishi, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682234/ https://www.ncbi.nlm.nih.gov/pubmed/26673416 http://dx.doi.org/10.1186/s12885-015-1975-5

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