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Expression of mouse CD47 on human cancer cells profoundly increases tumor metastasis in murine models
BACKGROUND: Many commonly used xenograft tumor models do not spontaneously metastasize to distant organs following subcutaneous or orthotopic implantation, limiting their usefulness in preclinical studies. It is generally believed that natural killer cells are the key component of the innate immune...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682254/ https://www.ncbi.nlm.nih.gov/pubmed/26674012 http://dx.doi.org/10.1186/s12885-015-1980-8 |