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Synergism of MSC-secreted HGF and VEGF in stabilising endothelial barrier function upon lipopolysaccharide stimulation via the Rac1 pathway

BACKGROUND: Mesenchymal stem cells (MSCs) stabilise endothelial barrier function in acute lung injury via paracrine hepatocyte growth factor (HGF). Vascular endothelial growth factor (VEGF), which is secreted by MSCs, is another key regulator of endothelial permeability; however, its role in adjusti...

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Detalles Bibliográficos
Autores principales:	Yang, Yi, Chen, Qi-hong, Liu, Ai-ran, Xu, Xiu-ping, Han, Ji-bin, Qiu, Hai-bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682264/ https://www.ncbi.nlm.nih.gov/pubmed/26674641 http://dx.doi.org/10.1186/s13287-015-0257-0

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