Partial PTEN deletion is linked to poor prognosis in breast cancer

BACKGROUND: Deletions of chromosome 10q23, including the PTEN (phosphatase and tensin homolog) locus, are known to occur in breast cancer, but systematic analyses of its clinical relevance are lacking. METHODS: We thus analyzed a tissue microarray (TMA) with 2,197 breast cancers by fluorescence in-s...

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Detalles Bibliográficos
Autores principales: Lebok, P., Kopperschmidt, V., Kluth, M., Hube-Magg, C., Özden, C., B., Taskin, Hussein, K., Mittenzwei, A., Lebeau, A., Witzel, I., Wölber, L., Mahner, S., Jänicke, F., Geist, S., Paluchowski, P., Wilke, C., Heilenkötter, U., Simon, Ronald, Sauter, Guido, Terracciano, L., Krech, R., von d. Assen, A., Müller, V., Burandt, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682275/
https://www.ncbi.nlm.nih.gov/pubmed/26672755
http://dx.doi.org/10.1186/s12885-015-1770-3

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