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Non-genetic Purification of Ventricular Cardiomyocytes from Differentiating Embryonic Stem Cells through Molecular Beacons Targeting IRX-4

Isolation of ventricular cardiomyocytes (vCMs) has been challenging due to the lack of specific surface markers. Here we show that vCMs can be purified from differentiating mouse embryonic stem cells (mESCs) using molecular beacons (MBs) targeting specific intracellular mRNAs. We designed MBs (IRX4...

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Detalles Bibliográficos
Autores principales: Ban, Kiwon, Wile, Brian, Cho, Kyu-Won, Kim, Sangsung, Song, Ming-Ke, Kim, Sang Yoon, Singer, Jason, Syed, Anum, Yu, Shan Ping, Wagner, Mary, Bao, Gang, Yoon, Young-sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682289/
https://www.ncbi.nlm.nih.gov/pubmed/26651608
http://dx.doi.org/10.1016/j.stemcr.2015.10.021

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