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Fibroblast Growth Factors and Vascular Endothelial Growth Factor Promote Cardiac Reprogramming under Defined Conditions
Fibroblasts can be directly reprogrammed into cardiomyocyte-like cells (iCMs) by overexpression of cardiac transcription factors, including Gata4, Mef2c, and Tbx5; however, this process is inefficient under serum-based culture conditions, in which conversion of partially reprogrammed cells into full...
Autores principales: | Yamakawa, Hiroyuki, Muraoka, Naoto, Miyamoto, Kazutaka, Sadahiro, Taketaro, Isomi, Mari, Haginiwa, Sho, Kojima, Hidenori, Umei, Tomohiko, Akiyama, Mizuha, Kuishi, Yuki, Kurokawa, Junko, Furukawa, Tetsushi, Fukuda, Keiichi, Ieda, Masaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682292/ https://www.ncbi.nlm.nih.gov/pubmed/26626177 http://dx.doi.org/10.1016/j.stemcr.2015.10.019 |
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