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Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel

Activation of mechanosensitive ion channels by physical force underlies many physiological processes including the sensation of touch, hearing and pain(1–5). TRAAK ion channels are neuronally expressed members of the two-pore domain K(+) (K2P) channel family and are mechanosensitive(6). They are inv...

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Detalles Bibliográficos
Autores principales:	Brohawn, Stephen G., Campbell, Ernest B., MacKinnon, Roderick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682367/ https://www.ncbi.nlm.nih.gov/pubmed/25471887 http://dx.doi.org/10.1038/nature14013

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