A two-layered machine learning method to identify protein O-GlcNAcylation sites with O-GlcNAc transferase substrate motifs

Protein O-GlcNAcylation, involving the β-attachment of single N-acetylglucosamine (GlcNAc) to the hydroxyl group of serine or threonine residues, is an O-linked glycosylation catalyzed by O-GlcNAc transferase (OGT). Molecular level investigation of the basis for OGT's substrate specificity shou...

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Detalles Bibliográficos
Autores principales: Kao, Hui-Ju, Huang, Chien-Hsun, Bretaña, Neil Arvin, Lu, Cheng-Tsung, Huang, Kai-Yao, Weng, Shun-Long, Lee, Tzong-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682369/
https://www.ncbi.nlm.nih.gov/pubmed/26680539
http://dx.doi.org/10.1186/1471-2105-16-S18-S10

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