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A systematic analysis of a broadly neutralizing antibody AR3C epitopes on Hepatitis C virus E2 envelope glycoprotein and their cross-reactivity

BACKGROUND: Hepatitis C virus (HCV) belongs to Flaviviridae family of viruses. HCV represents a major challenge to public health since its estimated global prevalence is 2.8% of the world's human population. The design and development of HCV vaccine has been hampered by rapid evolution of viral...

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Detalles Bibliográficos
Autores principales: Sun, Jing, Brusic, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682370/
https://www.ncbi.nlm.nih.gov/pubmed/26681161
http://dx.doi.org/10.1186/1755-8794-8-S4-S6