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A computational method for identification of vaccine targets from protein regions of conserved human leukocyte antigen binding

BACKGROUND: Computational methods for T cell-based vaccine target discovery focus on selection of highly conserved peptides identified across pathogen variants, followed by prediction of their binding of human leukocyte antigen molecules. However, experimental studies have shown that T cells often t...

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Detalles Bibliográficos
Autores principales:	Olsen, Lars R, Simon, Christian, Kudahl, Ulrich J, Bagger, Frederik O, Winther, Ole, Reinherz, Ellis L, Zhang, Guang L, Brusic, Vladimir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682376/ https://www.ncbi.nlm.nih.gov/pubmed/26679766 http://dx.doi.org/10.1186/1755-8794-8-S4-S1

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