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Multiple target drug cocktail design for attacking the core network markers of four cancers using ligand-based and structure-based virtual screening methods

BACKGROUND: Computer-aided drug design has a long history of being applied to discover new molecules to treat various cancers, but it has always been focused on single targets. The development of systems biology has let scientists reveal more hidden mechanisms of cancers, but attempts to apply syste...

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Detalles Bibliográficos
Autores principales:	Wong, Yung-Hao, Lin, Chih-Lung, Chen, Ting-Shou, Chen, Chien-An, Jiang, Pei-Shin, Lai, Yi-Hua, Chu, Lichieh Julie, Li, Cheng-Wei, Chen, Jeremy JW, Chen, Bor-Sen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682379/ https://www.ncbi.nlm.nih.gov/pubmed/26680552 http://dx.doi.org/10.1186/1755-8794-8-S4-S4

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