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Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia
Streptococcus (S.) pneumoniae is the most common causative pathogen in community-acquired pneumonia. Nucleotide-binding oligomerization domain-containing (NOD) 2 is a pattern recognition receptor located in the cytosol of myeloid cells that is able to detect peptidoglycan fragments of S. pneumoniae....
Autores principales: | Hommes, Tijmen J., van Lieshout, Miriam H., van ‘t Veer, Cornelis, Florquin, Sandrine, Bootsma, Hester J., Hermans, Peter W., de Vos, Alex F., van der Poll, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682639/ https://www.ncbi.nlm.nih.gov/pubmed/26673231 http://dx.doi.org/10.1371/journal.pone.0145138 |
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