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Subcritical Water Hydrolysis Effectively Reduces the In Vitro Seeding Activity of PrP(Sc) but Fails to Inactivate the Infectivity of Bovine Spongiform Encephalopathy Prions
The global outbreak of bovine spongiform encephalopathy (BSE) has been attributed to the recycling of contaminated meat and bone meals (MBMs) as feed supplements. The use of MBMs has been prohibited in many countries; however, the development of a method for inactivating BSE prions could enable the...
Autores principales: | Murayama, Yuichi, Yoshioka, Miyako, Okada, Hiroyuki, Takata, Eri, Masujin, Kentaro, Iwamaru, Yoshifumi, Shimozaki, Noriko, Yamamura, Tomoaki, Yokoyama, Takashi, Mohri, Shirou, Tsutsumi, Yuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682654/ https://www.ncbi.nlm.nih.gov/pubmed/26675475 http://dx.doi.org/10.1371/journal.pone.0144761 |
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