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Tissue-Specific Differences in DNA Modifications (5-Hydroxymethylcytosine, 5-Formylcytosine, 5-Carboxylcytosine and 5-Hydroxymethyluracil) and Their Interrelationships
BACKGROUND: Replication-independent active/enzymatic demethylation may be an important process in the functioning of somatic cells. The most plausible mechanisms of active 5-methylcytosine demethylation, leading to activation of previously silenced genes, involve ten-eleven translocation (TET) prote...
Autores principales: | Gackowski, Daniel, Zarakowska, Ewelina, Starczak, Marta, Modrzejewska, Martyna, Olinski, Ryszard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682766/ https://www.ncbi.nlm.nih.gov/pubmed/26660343 http://dx.doi.org/10.1371/journal.pone.0144859 |
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