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Mining Chemical Activity Status from High-Throughput Screening Assays

High-throughput screening (HTS) experiments provide a valuable resource that reports biological activity of numerous chemical compounds relative to their molecular targets. Building computational models that accurately predict such activity status (active vs. inactive) in specific assays is a challe...

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Detalles Bibliográficos
Autores principales: Soufan, Othman, Ba-alawi, Wail, Afeef, Moataz, Essack, Magbubah, Rodionov, Valentin, Kalnis, Panos, Bajic, Vladimir B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682830/
https://www.ncbi.nlm.nih.gov/pubmed/26658480
http://dx.doi.org/10.1371/journal.pone.0144426