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Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-Mediated Transrepression

Glucocorticoid signaling regulates target genes by multiple mechanisms, including the repression of transcriptional activities of nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) though direct protein-protein interactions and subsequent O-GlcNAcylation of RNA polymerase II (pol II)...

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Detalles Bibliográficos
Autores principales:	Stivers, Peter J., Harmonay, Lauren, Hicks, Alexandra, Mehmet, Huseyin, Morris, Melody, Robinson, Gain M., Strack, Peter R., Savage, Mary J., Zaller, Dennis M., Zwierzynski, Izabela, Brandish, Philip E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682863/ https://www.ncbi.nlm.nih.gov/pubmed/26670328 http://dx.doi.org/10.1371/journal.pone.0145151

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