CARD9-Dependent Neutrophil Recruitment Protects against Fungal Invasion of the Central Nervous System

Candida is the most common human fungal pathogen and causes systemic infections that require neutrophils for effective host defense. Humans deficient in the C-type lectin pathway adaptor protein CARD9 develop spontaneous fungal disease that targets the central nervous system (CNS). However, how CARD...

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Detalles Bibliográficos
Autores principales: Drummond, Rebecca A., Collar, Amanda L., Swamydas, Muthulekha, Rodriguez, Carlos A., Lim, Jean K., Mendez, Laura M., Fink, Danielle L., Hsu, Amy P., Zhai, Bing, Karauzum, Hatice, Mikelis, Constantinos M., Rose, Stacey R., Ferre, Elise M. N., Yockey, Lynne, Lemberg, Kimberly, Kuehn, Hye Sun, Rosenzweig, Sergio D., Lin, Xin, Chittiboina, Prashant, Datta, Sandip K., Belhorn, Thomas H., Weimer, Eric T., Hernandez, Michelle L., Hohl, Tobias M., Kuhns, Douglas B., Lionakis, Michail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683065/
https://www.ncbi.nlm.nih.gov/pubmed/26679537
http://dx.doi.org/10.1371/journal.ppat.1005293

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