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Towards understanding the roles of position and geometry on cell fate decisions during preimplantation development

The first lineage segregation event in mouse embryos produces two separate cell populations: inner cell mass and trophectoderm. This is understood to be brought about by cells sensing their position within the embryo and differentiating accordingly. The cellular and molecular underpinnings of this p...

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Detalles Bibliográficos
Autores principales: Biggins, John S., Royer, Christophe, Watanabe, Tomoko, Srinivas, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683091/
https://www.ncbi.nlm.nih.gov/pubmed/26349030
http://dx.doi.org/10.1016/j.semcdb.2015.09.006