Alternate RASSF1 Transcripts Control SRC Activity, E-Cadherin Contacts, and YAP-Mediated Invasion

Tumor progression to invasive carcinoma is associated with activation of SRC family kinase (SRC, YES, FYN) activity and loss of cellular cohesion. The hippo pathway-regulated cofactor YAP1 supports the tumorigenicity of RAS mutations but requires both inactivation of hippo signaling and YES-mediated...

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Detalles Bibliográficos
Autores principales: Vlahov, Nikola, Scrace, Simon, Soto, Manuel Sarmiento, Grawenda, Anna M., Bradley, Leanne, Pankova, Daniela, Papaspyropoulos, Angelos, Yee, Karen S., Buffa, Francesca, Goding, Colin R., Timpson, Paul, Sibson, Nicola, O’Neill, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683097/
https://www.ncbi.nlm.nih.gov/pubmed/26549256
http://dx.doi.org/10.1016/j.cub.2015.09.072

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