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Differences in the performance of NK1R−/− (‘knockout’) and wildtype mice in the 5‑Choice Continuous Performance Test

Mice lacking functional NK1 (substance P-preferring) receptors typically display excessive inattentiveness (omission errors) and impulsivity (premature responses) when compared with wildtypes in the 5-Choice Serial Reaction-Time Test (5-CSRTT). These abnormal behaviours are analogous to those seen i...

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Detalles Bibliográficos
Autores principales: Porter, Ashley J., Pillidge, Katharine, Stanford, S. Clare, Young, Jared W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683099/
https://www.ncbi.nlm.nih.gov/pubmed/26522842
http://dx.doi.org/10.1016/j.bbr.2015.10.045