Interaction of Iron II Complexes with B-DNA. Insights from Molecular Modeling, Spectroscopy, and Cellular Biology

We report the characterization of the interaction between B-DNA and three terpyridin iron II complexes. Relatively long time-scale molecular dynamics (MD) is used in order to characterize the stable interaction modes. By means of molecular modeling and UV-vis spectroscopy, we prove that they may lea...

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Detalles Bibliográficos
Autores principales: Gattuso, Hugo, Duchanois, Thibaut, Besancenot, Vanessa, Barbieux, Claire, Assfeld, Xavier, Becuwe, Philippe, Gros, Philippe C., Grandemange, Stephanie, Monari, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683171/
https://www.ncbi.nlm.nih.gov/pubmed/26734600
http://dx.doi.org/10.3389/fchem.2015.00067

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