Cargando…

Alternatively Spliced Isoforms of K(V)10.1 Potassium Channels Modulate Channel Properties and Can Activate Cyclin-dependent Kinase in Xenopus Oocytes

K(V)10.1 is a voltage-gated potassium channel expressed selectively in the mammalian brain but also aberrantly in cancer cells. In this study we identified short splice variants of K(V)10.1 resulting from exon-skipping events (E65 and E70) in human brain and cancer cell lines. The presence of the va...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ramos Gomes, Fernanda, Romaniello, Vincenzo, Sánchez, Araceli, Weber, Claudia, Narayanan, Pratibha, Psol, Maryna, Pardo, Luis A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2015
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683259/ https://www.ncbi.nlm.nih.gov/pubmed/26518875 http://dx.doi.org/10.1074/jbc.M115.668749

Ejemplares similares

Dihydropyridine Action on Voltage-dependent Potassium Channels Expressed in Xenopus Oocytes
por: Avdonin, Vladimir, et al.
Publicado: (1997)

Cyclic expression of the voltage‐gated potassium channel K(V)10.1 promotes disassembly of the primary cilium
por: Sánchez, Araceli, et al.
Publicado: (2016)

Expression of epithelial Na channels in Xenopus oocytes
Publicado: (1990)

Unidirectional K+ fluxes through recombinant Shaker potassium channels expressed in single Xenopus oocytes
Publicado: (1996)

Function of Shaker potassium channels produced by cell-free translation upon injection into Xenopus oocytes
por: Jarecki, Brian W., et al.
Publicado: (2013)

Inactivation of cloned Na channels expressed in Xenopus oocytes
Publicado: (1990)

Surface Charges of K channels. Effects of strontium on five cloned channels expressed in Xenopus oocytes
Publicado: (1996)

Xenopus oocyte maturation does not require new cyclin synthesis
Publicado: (1991)

PIST (GOPC) modulates the oncogenic voltage-gated potassium channel K(V)10.1
por: Herrmann, Solveig, et al.
Publicado: (2013)

Protease Modulation of the Activity of the Epithelial Sodium Channel Expressed in Xenopus Oocytes
por: Chraïbi, Ahmed, et al.
Publicado: (1998)

Expression and characterization of the bacterial mechanosensitive channel MscS in Xenopus laevis oocytes
por: Maksaev, Grigory, et al.
Publicado: (2011)

Cortactin Controls Surface Expression of the Voltage-gated Potassium Channel K(V)10.1
por: Herrmann, Solveig, et al.
Publicado: (2012)

Guiding TRAIL to cancer cells through Kv10.1 potassium channel overcomes resistance to doxorubicin
por: Hartung, Franziska, et al.
Publicado: (2016)

In vivo imaging of tumour xenografts with an antibody targeting the potassium channel K(v)10.1
por: Napp, Joanna, et al.
Publicado: (2016)

Mammalian Brain Ca(2+) Channel Activity Transplanted into Xenopus laevis Oocytes
por: Rousset, Matthieu, et al.
Publicado: (2022)

Asbestos Fibers Enhance the TMEM16A Channel Activity in Xenopus Oocytes
por: Bernareggi, Annalisa, et al.
Publicado: (2023)

Functional K(V)10.1 Channels Localize to the Inner Nuclear Membrane
por: Chen, Ye, et al.
Publicado: (2011)

Inhibition of Kv10.1 Channels Sensitizes Mitochondria of Cancer Cells to Antimetabolic Agents
por: Hernández-Reséndiz, Ileana, et al.
Publicado: (2020)

The Polarization of the G-Protein Activated Potassium Channel GIRK5 to the Vegetal Pole of Xenopus laevis Oocytes Is Driven by a Di-Leucine Motif
por: Díaz-Bello, Beatriz, et al.
Publicado: (2013)

Overexpression of Eag1 potassium channels in clinical tumours
por: Hemmerlein, Bernhard, et al.
Publicado: (2006)

Analysis of the expression of Kv10.1 potassium channel in patients with brain metastases and glioblastoma multiforme: impact on survival
por: Martínez, Ramón, et al.
Publicado: (2015)

Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channels
por: Cristofori-Armstrong, Ben, et al.
Publicado: (2015)

Channel properties of the splicing isoforms of the olfactory calcium-activated chloride channel Anoctamin 2
por: Ponissery Saidu, Samsudeen, et al.
Publicado: (2014)

Channel properties of the splicing isoforms of the olfactory calcium-activated chloride channel Anoctamin 2
por: Ponissery Saidu, Samsudeen, et al.
Publicado: (2013)

Single Channel Properties of Rat Acid–sensitive Ion Channel-1α, -2a, and -3 Expressed in Xenopus Oocytes
por: Zhang, Ping, et al.
Publicado: (2002)

Synthesis of novel purpurealidin analogs and evaluation of their effect on the cancer-relevant potassium channel K(V)10.1
por: Moreels, Lien, et al.
Publicado: (2017)

A Voltage Dependent Non-Inactivating Na(+) Channel Activated during Apoptosis in Xenopus Oocytes
por: Englund, Ulrika H., et al.
Publicado: (2014)

I–J loop involvement in the pharmacological profile of CLC-K channels expressed in Xenopus oocytes
por: Gradogna, Antonella, et al.
Publicado: (2014)

Recording Sodium Self-Inhibition of Epithelial Sodium Channels Using Automated Electrophysiology in Xenopus Oocytes
por: Lawong, Rene Y., et al.
Publicado: (2023)

Internal Na+ and Mg2+ blockade of DRK1 (Kv2.1) potassium channels expressed in Xenopus oocytes. Inward rectification of a delayed rectifier
Publicado: (1994)

Cftr: Covalent Modification of Cysteine-Substituted Channels Expressed in Xenopus Oocytes Shows That Activation Is Due to the Opening of Channels Resident in the Plasma Membrane
por: Liu, Xuehong, et al.
Publicado: (2001)

When Is a Potassium Channel Not a Potassium Channel?
por: Accili, Eric
Publicado: (2022)

Spliced isoforms of the cardiac Nav1.5 channel modify channel activation by distinct structural mechanisms
por: Mancino, Adamo S., et al.
Publicado: (2022)

Intracellular hemin is a potent inhibitor of the voltage-gated potassium channel Kv10.1
por: Sahoo, Nirakar, et al.
Publicado: (2022)

Single channel properties of mitochondrial large conductance potassium channel formed by BK-VEDEC splice variant
por: Gałecka, Shur, et al.
Publicado: (2021)

Expression of multiple water channel activities in Xenopus oocytes injected with mRNA from rat kidney
Publicado: (1993)

The Acrylamide (S)-2 As a Positive and Negative Modulator of Kv7 Channels Expressed in Xenopus laevis Oocytes
por: Blom, Sigrid Marie, et al.
Publicado: (2009)

Influenza D virus M2 protein exhibits ion channel activity in Xenopus laevis oocytes
por: Kesinger, Evan, et al.
Publicado: (2018)

Oxidized Glutathione Increases Delta-Subunit Expressing Epithelial Sodium Channel Activity in Xenopus laevis Oocytes
por: Grant, Garett J., et al.
Publicado: (2020)

Actin in Xenopus oocytes
Publicado: (1978)

Cannot write session to /tmp/vufind_sessions/sess_0oc17ifj41t5l3tsn4lm7a33m9