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Time lapse imaging analysis of the effect of ER stress modulators on apoptotic cell assessed by caspase3/7 activation in NG108-15 cells
This paper reports the data from the long term time lapse imaging of neuronal cell line NG108-15 that were treated with apoptosis inducer or various ER stress inducers. Use of the fluorescent reporter for activated caspase3/7 in combination with the conventional light microscope allowed us to invest...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683324/ https://www.ncbi.nlm.nih.gov/pubmed/26759824 http://dx.doi.org/10.1016/j.dib.2015.11.030 |
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author | Saito, Ayako Suga, Kei Ono-Nakagawa, Risa Sanada, Masumi Akagawa, Kimio |
author_facet | Saito, Ayako Suga, Kei Ono-Nakagawa, Risa Sanada, Masumi Akagawa, Kimio |
author_sort | Saito, Ayako |
collection | PubMed |
description | This paper reports the data from the long term time lapse imaging of neuronal cell line NG108-15 that were treated with apoptosis inducer or various ER stress inducers. Use of the fluorescent reporter for activated caspase3/7 in combination with the conventional light microscope allowed us to investigate the time course of apoptosis induction at the single cell level. Quantitative as well as qualitative data are presented here to show the effect of two different ER stress modulating chemical compounds on caspase3/7-dependent apoptosis in neuronal cell line NG108-15 cells. Additional results and interpretation of our data concerning ER stress and apoptosis in NG108-15 cells can be found in Suga et al. (2015) [1] and in Suga et al. (2015) [2]. |
format | Online Article Text |
id | pubmed-4683324 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-46833242016-01-12 Time lapse imaging analysis of the effect of ER stress modulators on apoptotic cell assessed by caspase3/7 activation in NG108-15 cells Saito, Ayako Suga, Kei Ono-Nakagawa, Risa Sanada, Masumi Akagawa, Kimio Data Brief Data Article This paper reports the data from the long term time lapse imaging of neuronal cell line NG108-15 that were treated with apoptosis inducer or various ER stress inducers. Use of the fluorescent reporter for activated caspase3/7 in combination with the conventional light microscope allowed us to investigate the time course of apoptosis induction at the single cell level. Quantitative as well as qualitative data are presented here to show the effect of two different ER stress modulating chemical compounds on caspase3/7-dependent apoptosis in neuronal cell line NG108-15 cells. Additional results and interpretation of our data concerning ER stress and apoptosis in NG108-15 cells can be found in Suga et al. (2015) [1] and in Suga et al. (2015) [2]. Elsevier 2015-11-21 /pmc/articles/PMC4683324/ /pubmed/26759824 http://dx.doi.org/10.1016/j.dib.2015.11.030 Text en © 2015 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Data Article Saito, Ayako Suga, Kei Ono-Nakagawa, Risa Sanada, Masumi Akagawa, Kimio Time lapse imaging analysis of the effect of ER stress modulators on apoptotic cell assessed by caspase3/7 activation in NG108-15 cells |
title | Time lapse imaging analysis of the effect of ER stress modulators on apoptotic cell assessed by caspase3/7 activation in NG108-15 cells |
title_full | Time lapse imaging analysis of the effect of ER stress modulators on apoptotic cell assessed by caspase3/7 activation in NG108-15 cells |
title_fullStr | Time lapse imaging analysis of the effect of ER stress modulators on apoptotic cell assessed by caspase3/7 activation in NG108-15 cells |
title_full_unstemmed | Time lapse imaging analysis of the effect of ER stress modulators on apoptotic cell assessed by caspase3/7 activation in NG108-15 cells |
title_short | Time lapse imaging analysis of the effect of ER stress modulators on apoptotic cell assessed by caspase3/7 activation in NG108-15 cells |
title_sort | time lapse imaging analysis of the effect of er stress modulators on apoptotic cell assessed by caspase3/7 activation in ng108-15 cells |
topic | Data Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683324/ https://www.ncbi.nlm.nih.gov/pubmed/26759824 http://dx.doi.org/10.1016/j.dib.2015.11.030 |
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