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Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells

Kindlins are FERM-containing cytoplasmic proteins that regulate integrin-mediated cell-cell and cell-extracellular matrix (ECM) attachments. Kindlin-3 is expressed in hematopoietic cells, platelets, and endothelial cells. Studies have shown that kindlin-3 stabilizes cell adhesion mediated by ß1, ß2,...

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Detalles Bibliográficos
Autores principales: Qu, Jing, Ero, Rya, Feng, Chen, Ong, Li-Teng, Tan, Hui-Foon, Lee, Hui-Shan, Ismail, Muhammad HB, Bu, Wen-Ting, Nama, Srikanth, Sampath, Prabha, Gao, Yong-Gui, Tan, Suet-Mien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683439/
https://www.ncbi.nlm.nih.gov/pubmed/26677948
http://dx.doi.org/10.1038/srep18491