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Bioinformatical parsing of folding-on-binding proteins reveals their compositional and evolutionary sequence design
Intrinsic disorder occurs when (part of) a protein remains unfolded during normal functioning. Intrinsically-disordered regions can contain segments that ‘fold on binding’ to another molecule. Here, we perform bioinformatical parsing of human ‘folding-on-binding’ (FB) proteins, into four subsets: Or...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683461/ https://www.ncbi.nlm.nih.gov/pubmed/26678310 http://dx.doi.org/10.1038/srep18586 |