Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion

Hematopoietic stem cells (HSCs) have emerged as promising therapeutic cell sources for high-risk hematological malignancies and immune disorders. However, their clinical use is limited by the inability to expand these cells ex vivo. Therefore, there is an urgent need to identify specific targets and...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Xiang-Qun, Yang, Peng, Zhang, Yu, Zhang, Peng, Wang, Liping, Ding, Yahui, Yang, Ming, Tong, Qin, Cheng, Haizi, Ji, Qing, McGuire, Terence, Yuan, Weiping, Cheng, Tao, Gao, Yingdai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683533/
https://www.ncbi.nlm.nih.gov/pubmed/26681454
http://dx.doi.org/10.1038/srep18115

Ejemplares similares

Ejemplares similares