Prion protein localizes at the ciliary base during neural and cardiovascular development, and its depletion affects α-tubulin post-translational modifications

Although conversion of the cellular form of the prion protein (PrP(C)) into a misfolded isoform is the underlying cause of prion diseases, understanding PrP(C) physiological functions has remained challenging. PrP(C) depletion or overexpression alters the proliferation and differentiation properties...

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Detalles Bibliográficos
Autores principales: Halliez, Sophie, Martin-Lannerée, Séverine, Passet, Bruno, Hernandez-Rapp, Julia, Castille, Johan, Urien, Céline, Chat, Sophie, Laude, Hubert, Vilotte, Jean-Luc, Mouillet-Richard, Sophie, Béringue, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683536/
https://www.ncbi.nlm.nih.gov/pubmed/26679898
http://dx.doi.org/10.1038/srep17146

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