Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance

The non-essential fatty acids, C18:1n9, C16:0, C16:1n7, C18:0 and C18:1n7 account for over 75% of fatty acids in white adipose (WAT) triacylglycerol (TAG). The relative composition of these fatty acids (FA) is influenced by the desaturases, SCD1-4 and the elongase, ELOVL6. In knock-out models, loss...

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Detalles Bibliográficos
Autores principales: Yew Tan, Chong, Virtue, Samuel, Murfitt, Steven, Robert, Lee D., Phua, Yi Hui, Dale, Martin, Griffin, Julian L., Tinahones, Francisco, Scherer, Philipp E., Vidal-Puig, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683622/
https://www.ncbi.nlm.nih.gov/pubmed/26679101
http://dx.doi.org/10.1038/srep18366

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