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SMRT Sequencing for Parallel Analysis of Multiple Targets and Accurate SNP Phasing
Single-molecule real-time (SMRT) sequencing generates much longer reads than other widely used next-generation (next-gen) sequencing methods, but its application to whole genome/exome analysis has been limited. Here, we describe the use of SMRT sequencing coupled with barcoding to simultaneously ana...
Autores principales: | Guo, Xiaoge, Lehner, Kevin, O’Connell, Karen, Zhang, Jenny, Dave, Sandeep S., Jinks-Robertson, Sue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683651/ https://www.ncbi.nlm.nih.gov/pubmed/26497143 http://dx.doi.org/10.1534/g3.115.023317 |
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