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Regionally-derived cell populations and skeletal stem cells from human foetal femora exhibit specific osteochondral and multi-lineage differentiation capacity in vitro and ex vivo

BACKGROUND: Adult skeletal stem cells (SSCs) often exhibit limited in vitro expansion with undesirable phenotypic changes and loss of differentiation capacity. Foetal tissues offer an alternative cell source, providing SSCs which exhibit desirable differentiation capacity over prolonged periods, ide...

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Detalles Bibliográficos
Autores principales:	Gothard, David, Cheung, Kelvin, Kanczler, Janos M., Wilson, David I., Oreffo, Richard O. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683700/ https://www.ncbi.nlm.nih.gov/pubmed/26684339 http://dx.doi.org/10.1186/s13287-015-0247-2

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