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Loss of intraepidermal nerve fiber density during SIV peripheral neuropathy is mediated by monocyte activation and elevated monocyte chemotactic proteins
BACKGROUND: Peripheral neuropathy (PN) continues to be a major complication of human immunodeficiency virus (HIV) infection despite successful anti-retroviral therapy. Human HIV-PN can be recapitulated in a CD8-depleted, simian immunodeficiency virus (SIV)-infected rhesus macaque animal model, chara...
Autores principales: | Lakritz, Jessica R., Robinson, Jake A., Polydefkis, Michael J., Miller, Andrew D., Burdo, Tricia H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683776/ https://www.ncbi.nlm.nih.gov/pubmed/26683323 http://dx.doi.org/10.1186/s12974-015-0456-8 |
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