Targeted tumor therapy by Rubia tinctorum L.: analytical characterization of hydroxyanthraquinones and investigation of their selective cytotoxic, adhesion and migration modulator effects on melanoma cell lines (A2058 and HT168-M1)

BACKGROUND: Alizarin and purpurin are di- and trihydroxyanthraquinones derived from Rubia tinctorum L. Previous pharmacological studies have demonstrated that they exhibit certain degree of selective inhibitory effects towards cancer cells suggesting their application as a targeted drug for cancer....

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Detalles Bibliográficos
Autores principales: Lajkó, Eszter, Bányai, Péter, Zámbó, Zsófia, Kursinszki, László, Szőke, Éva, Kőhidai, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683936/
https://www.ncbi.nlm.nih.gov/pubmed/26690297
http://dx.doi.org/10.1186/s12935-015-0271-4

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