Molecular analysis of pediatric brain tumors identifies microRNAs in pilocytic astrocytomas that target the MAPK and NF-κB pathways

INTRODUCTION: Pilocytic astrocytomas are slow-growing tumors that usually occur in the cerebellum or in the midline along the hypothalamic/optic pathways. The most common genetic alterations in pilocytic astrocytomas activate the ERK/MAPK signal transduction pathway, which is a major driver of proli...

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Detalles Bibliográficos
Autores principales: Jones, Tania A., Jeyapalan, Jennie N., Forshew, Tim, Tatevossian, Ruth G., Lawson, Andrew R. J., Patel, Sheena N., Doctor, Gabriel T., Mumin, Muhammad A., Picker, Simon R., Phipps, Kim P., Michalski, Antony, Jacques, Thomas S., Sheer, Denise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683939/
https://www.ncbi.nlm.nih.gov/pubmed/26682910
http://dx.doi.org/10.1186/s40478-015-0266-3

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