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Insulin–InsR signaling drives multipotent progenitor differentiation toward lymphoid lineages

The lineage commitment of HSCs generates balanced myeloid and lymphoid populations in hematopoiesis. However, the underlying mechanisms that control this process remain largely unknown. Here, we show that insulin–insulin receptor (InsR) signaling is required for lineage commitment of multipotent pro...

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Detalles Bibliográficos
Autores principales:	Xia, Pengyan, Wang, Shuo, Du, Ying, Huang, Guanling, Satoh, Takashi, Akira, Shizuo, Fan, Zusen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683997/ https://www.ncbi.nlm.nih.gov/pubmed/26573296 http://dx.doi.org/10.1084/jem.20150618

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