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Synthesis, characterization and antibacterial assessment of SiO(2)-hydroxypropylmethyl cellulose hybrid materials with embedded silver nanoparticles

Antibacterial SiO(2) hybrid materials based on tetraethyl orthosilicate (TEOS), hydroxypropylmethylcellulose (HPMC) and silver were prepared by the sol-gel method. The content of cellulose derivate was 5 wt% and the silver concentration varied from 0.5 wt% to 2.5 wt%. The amorphous nature, morpholog...

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Autores principales: Angelova, Tsvetelina, Rangelova, Nadezhda, Dineva, Hristina, Georgieva, Nelly, Müller, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684056/
https://www.ncbi.nlm.nih.gov/pubmed/26740774
http://dx.doi.org/10.1080/13102818.2014.944789
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author Angelova, Tsvetelina
Rangelova, Nadezhda
Dineva, Hristina
Georgieva, Nelly
Müller, Rudolf
author_facet Angelova, Tsvetelina
Rangelova, Nadezhda
Dineva, Hristina
Georgieva, Nelly
Müller, Rudolf
author_sort Angelova, Tsvetelina
collection PubMed
description Antibacterial SiO(2) hybrid materials based on tetraethyl orthosilicate (TEOS), hydroxypropylmethylcellulose (HPMC) and silver were prepared by the sol-gel method. The content of cellulose derivate was 5 wt% and the silver concentration varied from 0.5 wt% to 2.5 wt%. The amorphous nature, morphology and antibacterial behaviour were studied. Fourier transform infrared (FTIR) spectra of the hybrids showed characteristic peaks for SiO(2) network. Scanning electron microscope (SEM) analysis confirmed the formation of spherically shaped silver nanoparticles with a size of 30 nm on the matrix surfaces. Bacillus subtilis and Escherichia coli K12 were used as model microorganisms. The hybrid materials demonstrated bacteriostatic and bactericidal effect on the tested bacteria. Highest sensitivity to the obtained hybrids was observed in B. subtilis with significant lag-phase delay and biggest inhibition zone sizes.
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spelling pubmed-46840562016-01-04 Synthesis, characterization and antibacterial assessment of SiO(2)-hydroxypropylmethyl cellulose hybrid materials with embedded silver nanoparticles Angelova, Tsvetelina Rangelova, Nadezhda Dineva, Hristina Georgieva, Nelly Müller, Rudolf Biotechnol Biotechnol Equip Article; Pharmaceutical Biotechnology Antibacterial SiO(2) hybrid materials based on tetraethyl orthosilicate (TEOS), hydroxypropylmethylcellulose (HPMC) and silver were prepared by the sol-gel method. The content of cellulose derivate was 5 wt% and the silver concentration varied from 0.5 wt% to 2.5 wt%. The amorphous nature, morphology and antibacterial behaviour were studied. Fourier transform infrared (FTIR) spectra of the hybrids showed characteristic peaks for SiO(2) network. Scanning electron microscope (SEM) analysis confirmed the formation of spherically shaped silver nanoparticles with a size of 30 nm on the matrix surfaces. Bacillus subtilis and Escherichia coli K12 were used as model microorganisms. The hybrid materials demonstrated bacteriostatic and bactericidal effect on the tested bacteria. Highest sensitivity to the obtained hybrids was observed in B. subtilis with significant lag-phase delay and biggest inhibition zone sizes. Taylor & Francis 2014-07-04 2014-09-23 /pmc/articles/PMC4684056/ /pubmed/26740774 http://dx.doi.org/10.1080/13102818.2014.944789 Text en © 2014 The Author(s). Published by Taylor & Francis. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Article; Pharmaceutical Biotechnology
Angelova, Tsvetelina
Rangelova, Nadezhda
Dineva, Hristina
Georgieva, Nelly
Müller, Rudolf
Synthesis, characterization and antibacterial assessment of SiO(2)-hydroxypropylmethyl cellulose hybrid materials with embedded silver nanoparticles
title Synthesis, characterization and antibacterial assessment of SiO(2)-hydroxypropylmethyl cellulose hybrid materials with embedded silver nanoparticles
title_full Synthesis, characterization and antibacterial assessment of SiO(2)-hydroxypropylmethyl cellulose hybrid materials with embedded silver nanoparticles
title_fullStr Synthesis, characterization and antibacterial assessment of SiO(2)-hydroxypropylmethyl cellulose hybrid materials with embedded silver nanoparticles
title_full_unstemmed Synthesis, characterization and antibacterial assessment of SiO(2)-hydroxypropylmethyl cellulose hybrid materials with embedded silver nanoparticles
title_short Synthesis, characterization and antibacterial assessment of SiO(2)-hydroxypropylmethyl cellulose hybrid materials with embedded silver nanoparticles
title_sort synthesis, characterization and antibacterial assessment of sio(2)-hydroxypropylmethyl cellulose hybrid materials with embedded silver nanoparticles
topic Article; Pharmaceutical Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684056/
https://www.ncbi.nlm.nih.gov/pubmed/26740774
http://dx.doi.org/10.1080/13102818.2014.944789
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